Hematologic Disorders

Anemia of Chronic Disease

Braunstein, E. M. (2020). Anemia of chronic disease. Merck Manual. http://www.merckmanuals.com/professional/hematology-and-oncology/anemias-caused-by-deficient-erythropoiesis/anemia-of-chronic-disease

Domino, F. (Ed.). (2020). The 5-Minute Clinical Consult Standard 2020 (25th ed.) Wolters Kluwer.

Goroll, A. &. Mulley, A. (2020). Primary Care Medicine: Office Evaluation and Management of the Adult Patient (8th ed.). Wolters Kluwer.

Lanier, J. B., Park, J. P., & Callahan, R. C. (2018). Anemia in older adults. American Family Physician, 98(7), 437-442A. doi: 897563568

Sennett, M. M. (2017). Anemia. In T. M. Buttaro, J. Trybulski, P. Polgar-Baily, & J. Sandberg-Cook (Eds.). Primary Care: A Collaborative Practice. (5th Ed.). (pp. 1278-1297.). Elsevier.

Teke, H. U., Cansu, D. U., Yildiz, P., Temiz, G., & Bal, C. (2017). Clinical significance of serum IL6, hepcidin, and EPO levels in anemia of chronic disease and iron deficiency anemia: The laboratory indicators for anemia. Biomedical Research, 28(6), 2704-2710.

Weiss, G. (2015). Anemia of chronic disorders: new diagnostic tools and new treatment strategies. Seminars in Hematology, 52(4), 313-320. doi: 10.1053/j.seminhematol.2015.07.004

Folic Acid Deficiency

Argyridis, S. (2019). Folic acid in pregnancy. Obstetrics, Gynaecology & Reproductive Medicine, 29(4), 118-120. https://doi.org/10.1016/j.ogrm.2011.02.005

Coffey-Vega, K. (2018). Folic acid deficiency. Medscape. https://emedicine.medscape.com/article/200184

Cordero, A., Crider, K., Rogers, L., Cannon, M., & Berry, R. J. (2015). Optimal serum and red blood cell folate concentrations in women of reproductive age for prevention of neural tube defects: World Health Organization guidelines. Morbidity and Mortality Weekly Report, 64(15), 421-423. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6415a5.htm

Likis, F. (2016). Folic acid. Journal of Midwifery and Women’s Health, 61(5), 673-674. Doi: 10.1111/jmwh.12546

Moll, R., & Davis, B. (2017). Iron, vitamin B12 and folate. Medicine, 45(4), 198-203. Doi: 10.1016/j.mpmed.2017.01.007

U.S. Preventive Services Task Force. (2017). Folic acid supplementation for the prevention of neural tube defects: U.S. Preventive Services Task Force recommendation statement. JAMA, 317 (2) 183-189. Doi: 10.1001/jama.2016.19438

Glucose-6-Phosphate Dehydrogenase Deficiency

Bubp, J., Jen, M., Matuszewski, K. (2015). Caring for glucose-6-phosphate dehydrogenase (G6PD)-deficient patients: implications for pharmacy. Pharmacy & Therapeutics, 40(9), 572–574.

Liu, H., Liu, W., Tang, X., Wang, T. (2015). Association between G6PD deficiency and hyperbilirubinemia in neonates: a meta-analysis. Pediatric Hematology and Oncology, 32:92. doi: 10.3109/08880018.2014.887803

Nagala, S. (2020). Glucose-6-phosphate dehydrogenase deficiency. http://emedicine.medscape.com/article/200390-overview

National Library of Medicine. (2020). Glucose-6-phosphate dehydrogenase deficiency. https://ghr.nlm.nih.gov/condition/glucose-6-phosphate-dehydrogenase-deficiency#statistics

Richardson, S. R., & O'Malley, G. F. (2019). Glucose 6 phosphate dehydrogenase (G6PD) deficiency. Stat Pearls. https://www.ncbi.nlm.nih.gov/books/NBK470315/

Yang, W.C., Tai, S., Hsu, C. L., Fu, C. M., Chou, A. K., Shao, P. L., Li, M. J. (2020). Reference levels for glucose-6-phosphate dehydrogenase enzyme activity in infants 7-90 days old in Taiwan. Journal of the Formosa Medical Association. 119(1 Pt 1), 69-74. doi: 10.1016/j.jfma.2019.03.010

Human Immunodeficiency Virus

Centers for Disease Control and Prevention. (2020). HIV Surveillance Report: diagnosis of HIV infection in the United States and dependent areas. https://www.cdc.gov/hiv/statistics/overview/index.html

Centers for Disease Control and Prevention. (2019). HIV Basics. https://www.cdc.gov/hiv/basics/index.html

Centers for Disease Control and Prevention. (2018). 2018 Quick Reference Guide: Recommended laboratory testing algorithm for serum or plasma specimens. https://stacks.cdc.gov/view/cdc/50872

Centers for Disease Control and Prevention. (2016). Updated guidelines for antiretroviral postexposure prophylaxis after sexual, injection drug use, or other non-occupational exposure to HIV—United States, 2016. https://www.cdc.gov/hiv/pdf/programresources/cdc-hiv-npep-guidelines.pdf

Centers for Disease Control and Prevention. (2015). Sexually transmitted diseases treatment guidelines. https://www.cdc.gov/std/tg2015/default.htm

U.S. Department of Health and Human Services. Panel on Antiretroviral Guidelines for Adults and Adolescents. (2019). Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. https://aidsinfo.nih.gov/contentfiles/lvguidelines/AdultandAdolescentGL.pdf

U.S. Public Health Service. (2017). Preexposure prophylaxis for the prevention of HIV infection in the United States-2017 Update. https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2017.pdf

U.S. Public Health Service. (2018). Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HIV and Recommendations for Postexposure Prophylaxis. https://stacks.cdc.gov/view/cdc/20711

Immune Thrombocytopenia

Kessler, C. M. (2020). Immune thrombocytopenia purpura. Medscape. https://emedicine.medscape.com/article/202158-overview

Khan, A. M, Mydra, H. & Nevarez, A. (2017). Clinical practice updates in the management of immune thrombocytopenia. Pharmacy and Therapeutics, 42(12): 756-763. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720488/

Kuhne, T. (2017). Diagnosis and management of immune thrombocytopenia in childhood. Hamostaseologie, 37(1):36-44. doi: 10.5482/HAMO-16-06-0017

Mithoowani, S. & Arnold, D. (2019). First-line therapy for immune thrombocytopenia. Hamostaseologie, 39(3), 259-265. doi: 10.1055/s-0039-1684031

Silverman, M.A. (2017). Idiopathic thrombocytopenia purpura (ITP) in emergency medicine differential diagnoses. Medscape. https://emedicine.medscape.com/article/779545-differential

Iron Deficiency Anemia

BMJ Publishing Group. (2017). Iron Deficiency Anemia. BMJ Best Practice. http://bestpractice.bmj.com/topics/en-gb/94

Goroll, A. & Mulley, A.G. (2020). Primary Care Medicine: Office Evaluation and Management of the Adult Patient (8th ed.). Wolters Kluwer.

Harper, J. L. (2020). Iron deficiency anemia. Medscape. https://emedicine.medscape.com/article/202333

Hollier, A. (Ed.). (2018). Clinical Guidelines in Primary Care. (3rd ed.). Advanced Practice Education Associates.

Jimenez, K., Kulnigg-Dabsch, S., Gasche, C. (2015). Management of iron deficiency anemia. Gastroenterology and Hepatology 11(4), 241-250.

MPR Publications. (2020). Monthly Prescribing Reference. Haymarket Media.

Lead Toxicity

Agency for Toxic Substances & Disease Registry. (2019). Lead toxicity. How should patients exposed to lead be treated and managed? https://www.atsdr.cdc.gov/csem/csem.asp?csem=34&po=14

Centers for Disease Control & Prevention. (2019). Childhood lead poisoning prevention: Data and statistics. https://www.cdc.gov/nceh/lead/data/index.htm

Centers for Disease Control & Prevention. (2019). Childhood lead poisoning prevention: Laboratory considerations. https://www.cdc.gov/nceh/lead/lab/default.htm

Centers for Disease Control & Prevention. (2019). Childhood lead poisoning prevention: Lead poisoning prevention. https://www.cdc.gov/nceh/lead/prevention/default.htm

Council on Environmental Health. (2016). Prevention of childhood lead toxicity. Pediatrics, 138(1). DOI: https://doi.org/10.1542/peds.2016-1493

Pranay, K., Rowden, A., &O’Malley, R. (2020). Lead toxicity. Medscape. https://emedicine.medscape.com/article/1174752-overview


National Cancer Institute. (2020). Adult acute lymphoblastic leukemia treatment. http://www.cancer.gov/types/leukemia/hp/adult-all-treatment-pdq

National Cancer Institute. (2020). Adult acute myeloid leukemia treatment. http://www.cancer.gov/types/leukemia/hp/adult-aml-treatment-pdq

National Cancer Institute. (2017). Childhood acute lymphoblastic leukemia treatment. http://www.cancer.gov/types/leukemia/hp/child-all-treatment-pdq

National Cancer Institute. (2020). Childhood acute myeloid leukemia treatment. http://www.cancer.gov/types/leukemia/hp/child-aml-treatment-pdq

National Cancer Institute. (2020). Chronic lymphocytic leukemia treatment. http://www.cancer.gov/types/leukemia/hp/cll-treatment-pdq

National Cancer Institute. (2020). Chronic myelogenous leukemia treatment. http://www.cancer.gov/types/leukemia/hp/cml-treatment-pdq

National Cancer Institute. (2020). Hairy cell leukemia. http://www.cancer.gov/types/leukemia/hp/hairy-cell-treatment-pdq

Wu, L. (2019). Ophthalmologic manifestations of leukemias. Medscape. http://emedicine.medscape.com/article/1201870


Charpentier, A. M., Friedman, D. L., Wolden, S., et al. (2016). Predictive factor analysis of response-adapted radiation therapy for chemotherapy-sensitive pediatric Hodgkin lymphoma: analysis of the Children's Oncology Group AHOD 0031 Trial. International Journal of Radiation Oncology Biology and Physics, 96(5), 943-950. doi: 10.1016/j.ijrobp.2016.07.015

Friedman, D.L., Chen, L., Wolden, S., et al. (2014). Dose-intensive response-based chemotherapy and radiation therapy for children and adolescents with newly diagnosed intermediate-risk Hodgkin lymphoma: a report from the Children's Oncology Group Study AHOD0031. Journal of Clinical Oncology, 32(32), 3651-8. doi: 10.1200/JCO.2013.52.5410

Kline, N., Bryant, R., Carlson, C. Hooke, M. & Nixon, C. (2014). Essentials of Pediatric Hematology/Oncology Nursing: A Core Curriculum (4th ed.) Association of Pediatric Hematology/Oncology Nurses.

Lash, B. W. (2018). Hodgkin lymphoma. Medscape. https://emedicine.medscape.com/article/201886-overview

Rosolen, A., Perkins, S. L., Pinkerton, C. R., et al. (2015). Revised International Pediatric Non-Hodgkin Lymphoma Staging System. Journal of Clinical Oncology, 33(18), 2112-2118. doi: 10.1200/JCO.2014.59.7203

Sandlund, J. T., Guillerman, R. P., Perkins, S. L., et al. (2015). International pediatric non-Hodgkin lymphoma response criteria. Journal of Clinical Oncology, 33, 2106-2111. doi: 10.1200/JCO.2014.59.0745

Vinjamaram, S. (2019). Non-Hodgkin lymphoma. Medscape. https://emedicine.medscape.com/article/203399

Neonatal Hyperbilirubinemia

Akpan, U. et al. (2019). The hematopoietic system. In A. Jnah & A. Trembath (Eds). Fetal and Neonatal Physiology for the Advanced Practice Nurse. Springer Publishing.

American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. (2004). Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation, 114 (1), 297-316. doi.org/10.1542/peds.114.1.297

Bagwell, G. A. & Steward, D. K. (2020). Hematologic system. In C. Kenner, L. Altimier, & M. Boykova (Eds). Comprehensive Neonatal Nursing Care. Springer Publishing.

Hanson, T. (2017). Neonatal jaundice treatment and management. Medscape. https://emedicine.medscape.com/article/974786-treatment

Itoh, S., Okada, H., Kuboi, T. & Kusaka, T. (2017). Phototherapy for neonatal jaundice. Pediatrics International, 59, 959-966, doi: 10.1111/ped.13332

Mitra, S. & Rennie, J. (2017). Neonatal jaundice: aetiology, diagnosis and treatment. British Journal of Hospital Medicine, 78(12), 699-704. doi: 10.12968/hmed.2017.78.12.699

Polycythemia Vera

Arber, D. A., Orazi, A., Hasserjian, R., Thiele, J., Borowitz, M. J., Le Beau, M. M., Vardiman, J. W. (2016). The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 127(20), 2391-2405. https://doi.org/10.1182/blood-2016-03-643544

Jaffe, E. S., Arber, D. A., Campo, E., Harris, N. L., & Quintanilla-Martinez, L. (2017). Principles of classification of myeloid neoplasms. In Hematopathology. (2nd ed.). Elsevier.

McMullin, M. F., Harrison, C. N., Ali, S., Cargo, C., Chen, F., Ewing, J. … Mead, A. J. (2018). A guideline for the diagnosis and management of polycythemia vera. A British Society for Haematology guideline. British Journal of Haematology, 184, 176-191. doi: 10.1111/bjh.15648.

Prchal, J.F. & Prchal J.T. (2016). Polycythemia vera. In K. Kauschansky, et al. (Eds.) Williams Hematology. McGraw-Hill.

Tefferi, A., & Barbui, T. (2019). Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. American Journal of Hematology, 94(1), 162-173. doi: 10.1002/ajh.25303

Rh Incompatibility

Aitken, S. L. & Tichy, E. M. (2015). RhD immune globulin products for prevention of alloimmunization during pregnancy. American Journal of Health-System Pharmacy, 72, 267-276. doi.org/10.2146/ajhp140288

Akpan, U. et al. (2019). The hematopoietic system. In A. Jnah & A. Trembath (Eds). Fetal and Neonatal Physiology for the Advanced Practice Nurse. Springer Publishing.

Bagwell, G.A. & Steward, D.K. (2020). Hematologic system. In C. Kenner, L. Altimier, & M. Boykova (Eds). Comprehensive Neonatal Nursing Care. Springer Publishing.

Kedrion Biopharma. (2019). Rhogam prescribing information. http://www.rhogam.com/

Maisels, M. & Watchko, J. (2016). Jaundice. In M. MacDonald and M. Seshia (Eds). Avery’s Neonatology-Pathophysiology and Management of the Newborn. Wolters Kluwer.

Sickle Cell Anemia

Cennimo, D. (2019). Parvovirus B19 infection: background, pathophysiology, epidemiology. Medscape. http://emedicine.medscape.com/article/961063

Centers for Disease Control and Prevention. (2019). Sickle cell disease data & statistics. https://www.cdc.gov/ncbddd/sicklecell/data.html

Chou, S. T., Alsawas, M., Fasano, R. M., Field, J. J., Hendrickson, J. E., Howard, J., Kameka, M., Kwiatkowski, J. L., Pirenne, F., Ahi, P. A., Stowell, S. R., Thein, S. L., Westhoff, C. M., Wong, T. E., Akl, E. A. (2020). American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support. Blood Advances, 28(4), 327-355. DOI: 10.1182/bloodadvances.2019001143

Hollier, A. (Ed.). (2018). Sickle cell anemia. In Clinical Guidelines in Primary Care. (3rd ed.) Advanced Practice Education Associates.

Maakaron, J. (2020). Sickle cell anemia. Medscape. http://emedicine.medscape.com/article/205926

National Heart, Lung and Blood Institute. (2014). Evidence-based management of sickle cell disease: expert panel report, 2014. https://www.nhlbi.nih.gov/health-topics/evidence-based-management-sickle-cell-disease


Advani, P. (2019). Beta thalassemia. Medscape. https://emedicine.medscape.com/article/206490

Cheerva, A. C. (2018). Alpha thalassemia. Medscape. https://emedicine.medscape.com/article/955496-overview

Chonat, S. & Quinn, S. (2017). Current standards of care and long-term outcomes for thalassemia and sickle cell disease. Advances in Experimental Medicine and Biology, 1013(1), 59-87. DOI: 10.1007/978-1-4939-7299-9_3

Kline, N., Bryant, R., Carlson, C. Hooke, M. & Nixon, C. (2014). Essentials of Pediatric Hematology/Oncology Nursing: A Core Curriculum (4th ed.) Association of Pediatric Hematology/Oncology Nurses.

Lal, A. (2017). Assessment and treatment of pain in thalassemia. The New York Academy of Sciences, 1368(1), 65-72. doi: 10.1111/nyas.13061

Musallam, K. M., Taher, A. T., & Rachmilewitz, E. A. (2017). β-thalassemia intermedia: a clinical perspective. Cold Spring Harbor Perspectives in Medicine, 2(7), a013482. doi: 10.1101/cshperspect. a013482

Pepe, A., Meloni, A., Rossi, G., Caruso, V., Cuccia, L., Spasiano, A., Gamberini, M.R. (2017). Cardiac complications and diabetes in thalassemia major: a large historical multicenter study. European Heart Journal-Cardiovascular Imaging, 19(3), 299-309. doi: 10.1111/bjh.12557

Sleiman, J., Tarhini, A., & Bou-Fakhredin, R. (2018). Non-transfusion-dependent thalassemia: An update on complication and management. International Journal of Molecular Science, 19(1), 182. doi: 10.3390/ijms19010182.

Vichinsky, E. (2016). Non-transfusion-dependent thalassemia and thalassemia intermedia: epidemiology, complication, and management. Current Medical Research, 32(1), 191-204. doi: 10.1185/03007995.2015.1110128

Vitamin B12 Deficiency

Boucher, M., Bryan, S., & Dukes, S. (2015). Deficiency or dementia? Exploring B12 deficiency after urostomy. British Journal of Nursing, 24(11), 594-597. Doi:10.12968/bjon.2015.24.11.594

Hollier, A. (Ed.). Vitamin B12 deficiency. In Clinical Guidelines in Primary Care. (3rd ed.). Advanced Practice Education Associates.

Langan, R. C., & Goodbred, A. J. (2017). Vitamin B12 deficiency: recognition and management. American Family Physician, 96(6), 384-389. https://www.aafp.org/afp/2017/0915/p384.html

Shipton, M., & Thachil, J. (2015). Vitamin B12 deficiency – A 21st century perspective. Clinical Medicine, 15(2), 145-50. Doi:10.7861/clinmedicine.15-2-145.

Sukumar, N. (2019). Investigating vitamin B12 deficiency. BMJ 365, 1865. doi: 10.1136/bmj.l1865

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